Description
Mefenamic Acid
Pharmacokinetic:
Absorption: Usually reaches peak plasma levels 2 to 4 hrs after administration with a half-life of 2 hrs.
Mefenamic acid is a non- steroidal anti- inflammatory drug used to treat pain. Exhibits anti-inflammatory analgesic and Antipyretic. The mechanism of action of Mefenamic acid is similar to other NSAIDs.
Distribution: Mefenamic acid and its metabolites are firmly bound to plasma proteins.
Elimination: Following a single dose , 67% of the total dose is excreted in the urine as unchanged drug or as one of the two metabolites20%-25% of the dose is excreted in the faces during the first three days.
Children: 250 mg three times daily should be taken with food
Sujay –
good